Emlenoflast (MCC7840) sodium is a sulfonylurea-based NLRP3 inflammasome inhibitor (IC50 <100 nM) with anti-inflammatory activity. Inflammasomes are protein complexes which are important in several inflammatory diseases. Inflammasomes form part of the innate immune system that triggers the activation of inflammatory cytokines interleukin (IL)-1β and IL-18. The inflammasome most studied in sterile inflammation and non-communicable disease is the NLRP3 inflammasome.

纯度：≥98%

CAS：2380032-29-9