| CAS NO: | 22083-74-5 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
A nicotinic acetylcholine receptor (nAChR) agonist
| Cas No. | 22083-74-5 |
| 别名 | (+/-)-尼古丁,(±)-Nicotine |
| 化学名 | (R)-3-(1-methylpyrrolidin-2-yl)pyridine |
| Canonical SMILES | CN1[C@@H](C2=CC=CN=C2)CCC1 |
| 分子式 | C10H14N2 |
| 分子量 | 162.23 |
| 溶解度 | >6.8mg/mL in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 文献引用 | |
| 产品描述 | (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs; Kis = 481 and 11.1 nM for α3β4 and α4β2 subtypes, respectively) and possesses addictive and teratogenic properties.1 (–)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode, thus nicotine is typically synthesized as (–)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.2 |
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