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9(E),11(E)-12-nitro Conjugated Linoleic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
9(E),11(E)-12-nitro Conjugated Linoleic Acid图片
CAS NO:1515620-30-0
包装与价格：
包装价格(元)
50 μg电议
100 μg电议
250 μg电议
500 μg电议

产品介绍
A nitrated fatty acid
Cas No.1515620-30-0
Canonical SMILESCCCCCC/C([N+]([O-])=O)=C\C=C\CCCCCCCC(O)=O
分子式C18H31NO4
分子量325.4
溶解度0.1 M Na2CO3: 1mg/mL,DMF: 50mg/mL,DMSO: 50mg/mL,Ethanol: 50mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.

1.Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1)25-33(2014) 2.Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al.Conjugated linoleic acid is a preferential substrate for fatty acid nitrationJ. Biol. Chem.287(53)44071-44082(2012)