| CAS NO: | 1228182-47-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 1228182-47-5 |
| 别名 | 芬苯达唑 d3 |
| Canonical SMILES | O=C(OC([2H])([2H])[2H])NC1=NC2=CC(SC3=CC=CC=C3)=CC=C2N1 |
| 分子式 | C15H10D3N3O2S |
| 分子量 | 302.4 |
| 溶解度 | DMSO: slightly soluble,Methanol: slightly soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Fenbendazole-d3is intended for use as an internal standard for the quantification of fenbendazole by GC- or LC-MS. Fenbendazole is a benzimidazole anthelmintic.1It is active againstGiardia in vitro(IC50= 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model ofE. cuniculiinfection.2It also activates HIF-1α and prevents oxidative stress-induced death in primary neuronsin vitro.3 1.Morgan, U.M., Reynoldson, J.A., and Thompson, R.C.A.Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitroAntimicrob. Agents Chemother.37(2)328-331(1993) 2.Suter, C., MÜller-Doblies, U.U., Hatt, J.-M., et al.Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazoleVet. Rec. 148(15)478-480(2001) 3.Aleyasin, H., Karuppagounder, S.S., Kumar, A., et al.Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulinAntioxid. Redox Signal.22(2)121-134(2015) |
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