| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 分子式: | C15H12ClN3 |
| 分子量: | 269.73 |
| 纯度: | >98% |
| 溶解性: | DMSO : 200 mg/mL (741.48 mM; Need ultrasonic) |
| 存储: | 4℃, stored under nitrogen. In solvent : -80℃, 6 months; -20℃, 1 month (protect from light, stored under nitrogen) |
| 研究领域: | Cancer |
| Target: | IC50: 4.9 μM (hGWLFL), 4.9 μM (hGWL-KinDom) |
| 描述: | GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 μM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 μM, but only weakly affected PKA |
