| CAS NO: | 482333-74-4 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 482333-74-4 |
| 别名 | 糖精1-甲基咪唑 |
| 化学名 | 1-methyl-1H-imidazol-1-ium benzo[d]isothiazol-3-olate 1,1-dioxide |
| Canonical SMILES | [O-]C1=NS(C2=CC=CC=C21)(=O)=O.C[NH+]3C=CN=C3 |
| 分子式 | C11H11N3O3S |
| 分子量 | 265.29 |
| 溶解度 | DMF: 5mg/mL,DMSO: 5mg/mL,Ethanol: 10mg/mL,PBS (pH 7.2): 10mg/mL |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Saccharin 1-methylimidazole (SMI) is a DNA and RNA synthesis activator. Saccharin 1-methylimidazole (SMI) is the saccharin salt of 1-methylimidazole. 1-Methylimidazole or N-methylimidazole is identified as an aromatic heterocyclic organic agent with the formula CH3C3H3N2. 1-Methylimidazole is a colourless liquid that is used as a base, a specialty solvent, and as a precursor to some ionic liquids. 1-Methylimidazole is a fundamental nitrogen heterocycle and 1-methylimidazole mimics for a variety of nucleoside bases as well as histidine and histamine. In vitro: Saccharin 1-methylimidazole was found to be able to perform very well for DNA and RNA synthesis. In addition, by using 3 minute, 6 minute, and 12 minute coupling times, saccharin 1-methylimidazole was evaluated in RNA synthesis using TBDMS phosphoramidites, and the results found that a 6 minute coupling time for saccharin 1-methylimidazole showed ETT at a 6 minute coupling time. In additio, it was found that longer coupling times for Saccharin 1-methylimidazole could result in even further improvements in RNA coupling efficiencies [1]. In vivo: So far, there is no animal in vivo data reported for saccharin 1-methylimidazole. Clinical trial: Up to now, saccharin 1-methylimidazole is not used clinically. Reference: |
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