| CAS： | 212844-54-7 |
| 分子式： | C20H25ClN6O3 |
| 分子量： | 432.90 |
| 纯度： | >98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Cancer |
| Target： | IC50: 6 nM (cdc2/cyclin B),6 nM (cyclin dependent kinase 1-cyclinB),6 nM (cdk2/cyclin A),9 nM (CDK2/cyclinE),6 nM (CDK5/p35),1000 nM (Cdk4/cyclin D1),51 nM (CDK2/cyclinE), |
| 描述： | Purvalanol B (NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. |
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