| CAS NO: | 202808-11-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 20mg | 电议 |
| Cas No. | 202808-11-5 |
| Canonical SMILES | O=C1NNC(C2=C1C=C3C=C(Br)C=CC3=[N+]2[O-])=O |
| 分子式 | C11H6BrN3O3 |
| 分子量 | 308.09 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM. MRZ 2-514 has IC50 values against peak AMPA-induced currents of 72.7 μM[1]. MRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid[1]. [1]. Parsons CG, et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. Journal of Pharmacology and Experimental Therapeutics (1997), 283(3), 1264-1275 |
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