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Rimeporide hydrochloride(EMD-87580 hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Rimeporide hydrochloride(EMD-87580 hydrochloride)图片
CAS NO:187870-95-7
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Rimeporide hydrochloride (EMD-87580 hydrochloride) (EMD-87580 hydrochloride) 是 Na+/H+ 交换剂 (NHE-1) 的有效选择性抑制剂。
Cas No.187870-95-7
别名EMD-87580 hydrochloride
Canonical SMILESO=C(NC(N)=N)C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C.Cl
分子式C11H16ClN3O5S2
分子量369.84
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].

[1]. F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.