N-去甲基西地那非 (Desmethylsildenafil) 是西地那非的主要代谢物。
| Cas No. | 139755-82-1 |
| 别名 | N-去甲基西地那非,Desmethylsildenafil; UK-103,320 |
| Canonical SMILES | CCOC1=C(C2=NC(C(CCC)=NN3C)=C3C(N2)=O)C=C(C=C1)S(N4CCNCC4)(=O)=O |
| 分子式 | C21H28N6O4S |
| 分子量 | 460.6 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N-Desmethyl sildenafil is a major metabolite of sildenafil . N-Desmethyl sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7. |
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