| CAS NO: | 518303-20-3 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| CAS： | 518303-20-3 |
| 分子式： | C18H14BrNO5S2 |
| 分子量： | 468.34 |
| 纯度： | >98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Cancer |
| Target： | Ki: 0.49 μM (Mcl-1)[1], 5.33 μM (Bfl-1), 8.19 μM (Bcl-W), 23.83 μM (Bcl-2), 32.99 μM (Bcl-xL) |
| 描述： | UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other memb |
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