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α-Ecdysone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
α-Ecdysone图片
CAS NO:3604-87-3
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
α-Ecdysone (α-α-Ecdysone) 是昆虫和草药中的主要类固醇激素，可触发盐皮质激素受体 (MR) 激活并诱导细胞凋亡。
Cas No.3604-87-3
别名蜕皮激素; α-Ecdysone
化学名(5β)-2β,3β,14,22R,25-pentahydroxy-cholest-7-en-6-one
Canonical SMILESO=C1[C@]2([H])C[C@@H](O)[C@@H](O)C[C@]2(C)[C@]3([H])C([C@@](CC[C@@H]4[C@H](C)[C@H](O)CCC(C)(O)C)(O)[C@]4(C)CC3)=C1
分子式C27H44O6
分子量464.6
溶解度DMF: 2 mg/mL,DMSO: 0.1 mg/mL,Ethanol: 20 mg/mL,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

α-Ecdysone is a prohormone of 20-hydroxy ecdysone , an insect-molting, ecdysteroid hormone. The insect neurohormone, prothoracicotropic hormone, stimulates prothoracic glands to release α-ecdysone, which is then rapidly converted to its active metabolite, 20-hydroxy ecdysone.

Reference:
[1]. Fallon, A.M., and Gerenday, A. Ecdysone and the cell cycle: Investigations in a mosquito cell line. J.Insect Physiol. 56(10), 1396-1401 (2010).
[2]. Carrow, G.M., Calabrese, R.L., and Williams, C.M. Spontaneous and evoked release of prothoracicotropin from multiple neurohemal organs of the tobacco hornworm. Proceedings of the National Academy of Sciences of the United States of America 78(9), 5866-5870 (1981).
[3]. Cherbas, L., and Cherbas, P. Distribution and metabolism of α-ecdysone in pupae of the silkworm Antheraea Polyphemus. Biol.Bull. 138(2), 115-128 (1970).