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PF 750
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
PF 750图片
CAS NO:959151-50-9
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
PF 750 是一种选择性的共价脂肪酸酰胺水解酶 (FAAH) 抑制剂，在不同的预孵育时间，IC50 为 16.2-595 nM。
Cas No.959151-50-9
别名N-苯基-4-(3-喹啉基甲基)-1-哌啶甲酰胺
化学名N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
Canonical SMILESO=C(NC1=CC=CC=C1)N2CCC(CC3=CC4=CC=CC=C4N=C3)CC2
分子式C22H23N3O
分子量345.44
溶解度DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.125 mg/ml,Ethanol: 1 mg/ml
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].

References:
[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30.