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9,10-Dihydroxystearic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
9,10-Dihydroxystearic Acid图片
CAS NO:120-87-6
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
9,10-二羟基硬脂酸是油酸的氧化产物。
Cas No.120-87-6
别名9,10-二羟硬脂酸；9,10-二羟基十八酸
化学名9,10-dihydroxy-octadecanoic acid
Canonical SMILESOC(CCCCCCCC(O)C(O)CCCCCCCC)=O
分子式C18H36O4
分子量316.5
溶解度DMF: 25mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL,Ethanol: 5mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

9,10-Dihydroxystearic acid is an oxidation product of oleic acid that can be formed from oleic acid in HepG2 cells.[1] It activates peroxisome proliferator-activated receptor α (PPARα) in CV-1 cells when used at concentrations ranging from 50 to 100 μM.[2] 9,10-Dihydroxystearic acid (4% in the diet) decreases blood glucose levels, increases insulin sensitivity, and decreases body weight in high-fat diet-fed KKAy diabetic mice.

Reference:
[1]. Jing, H.-J., Zhang, Y.-H., Wang, J., et al. Conversion of oleic acid to 9,10-dihydroxystearic acid in human hepatic cancer HepG2 cells. Junyi Jinxiu Xueyuan Xuebao 31(6), 597-599 (2010).
[2]. Yu, X., Zhang, Y., Liu, Y., et al. Effects of 9,10-dihydroxysteatic acid on glucose metabolism in KKAy mice. Wei Sheng Yan Jiu 39(4), 423-425 (2010).