| CAS NO: | 1250-95-9 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 1250-95-9 |
| 别名 | 胆固醇-5Α,6Α-环氧化物,NSC 18176 |
| 化学名 | (3β,5α,6α)-5,6-epoxy-cholestan-3-ol |
| Canonical SMILES | C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C[C@H]4[C@@]5(O4)C[C@@H](O)CC[C@]5(C)[C@@]3([H])CC[C@@]21C |
| 分子式 | C27H46O2 |
| 分子量 | 402.7 |
| 溶解度 | ≤20mg/ml in ethanol; 0.1mg/ml in DMSO; 2mg/ml in dimethyl formamide |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5α,6α-epoxy Cholestanol is an oxysterol and a metabolite of cholesterol produced by oxidation.[1] 5α,6α-epoxy Cholestanol accumulates in MCF-7 breast cancer cells in a reactive oxygen species-dependent manner following tamoxifen and PBPE application and induces triacylglycerol biosynthesis by binding to liver x receptor β (LXRβ). [2] 5α,6α-epoxy Cholestanol levels are increased in rat aorta and mesenteric artery following orchidectomy, an effect that can be prevented by a DHA-supplemented diet.[1] Levels are also increased in post-mortem frontal and occipital cortex of patients with Alzheimer’s disease. [3] Reference: |
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