| CAS NO: | 129-43-1 |
| 包装 | 价格(元) |
| 1g | 电议 |
| 5g | 电议 |
| 10g | 电议 |
| 25g | 电议 |
| Cas No. | 129-43-1 |
| 别名 | 1-羟基蒽醌 |
| Canonical SMILES | O=C1C2=C(C(C3=C1C=CC=C3O)=O)C=CC=C2 |
| 分子式 | C14H8O3 |
| 分子量 | 224.2 |
| 溶解度 | Chloroform: 30 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 1-Hydroxyanthraquinone is an anthraquinone that has been found inMorinda officinalisand has genotoxic and carcinogenic activities.1,21-Hydroxyanthraquinone (5 and 500 µM) increases the percentage of isolated rat hepatocytes undergoing unscheduled DNA synthesis, indicating genotoxic activity.1Dietary administration of 1-hydroxyanthraquinone (1%) induces formation of cecum and colon adenocarcinomas, as well as hepatocellular carcinomas, in rats. 1.Kawai, K., Mori, H., Sugie, S., et al.Genotoxicity in the hepatocyte/DNA repair test and toxicity to liver mitochondria of 1-hydroxyanthraquinone and several dihydroxyanthraquinonesCell Biol. Toxicol.2(4)457-467(1986) 2.Mori, H., Yoshimi, N., Iwata, H., et al.Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: Induction of large bowel, liver and stomach neoplasmsCarcinogenesis11(5)799-802(1990) |
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