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Betulinic Aldehyde oxime
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Betulinic Aldehyde oxime图片
CAS NO:25613-12-1
包装与价格：
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
A derivative of betulin
Cas No.25613-12-1
别名桦木醛肟,半合成
Canonical SMILESON=C[C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC4)C)([H])CC3)C)C
分子式C30H49NO2
分子量455.7
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as well asL. donovaniamastigotes, when used at a concentration of 50 µM.1,2Betulinic aldehyde oxime (50 µM) is cytotoxic to Huh7 hepatocellular carcinoma cells.2

1.Alakurtti, S., BergstrÖm, P., Sacerdoti-Sierra, N., et al.Anti-leishmanial activity of betulin derivativesJ. Antibiot. (Tokyo)63(3)123-126(2010) 2.Haque, S., Nawrot, D.A., Alakurtti, S., et al.Screening and characterisation of antimicrobial properties of semisynthetic betulin derivativesPLoS One9(7)e102696(2014)