| CAS NO: | 1616413-96-7 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 25mg | 电议 |
| Cas No. | 1616413-96-7 |
| 别名 | (S)-4-(6-氨基-1-甲基-1H-吡唑并[3,4-D]嘧啶-4-基)-N-(4-甲氧基-2-甲基苯基)-3-甲基哌嗪-1-甲酰胺 |
| 化学名 | (S)-4-(6-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methylpiperazine-1-carboxamide |
| Canonical SMILES | CN1N=CC2=C(N3[C@@H](C)CN(C(NC4=CC=C(OC)C=C4C)=O)CC3)N=C(N)N=C21 |
| 分子式 | C20H26N8O2 |
| 分子量 | 410.482 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | UCB9608 (UCB-9608) is a potent, selective, orally bioavailable PI4KIIIβ inhibitor with IC50 of 11 nM; also shows an IC50 of 37 nM in the human mixed lymphocyte reaction (HuMLR) assay, only inhibits the PI4KIIIβ and PI3KC2 α, β and γ lipid kinases in apnel of 250 kinases tested at 10 uM; UCB9608 is vastly more soluble, selective compound with improved metabolic stability and excellent pharmacokinetic profile, significantly prolongs allogeneic organ engraftment in vivo. References: |
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