您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > (-)-(α)-Kainic Acid(hydrate)
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
(-)-(α)-Kainic Acid(hydrate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(-)-(α)-Kainic Acid(hydrate)图片
CAS NO:58002-62-3
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
A potent central nervous system stimulant for induction of seizures
Cas No.58002-62-3
别名红藻氨酸
化学名2S-carboxy-4S-(1-methylethenyl)-3S-pyrrolidineacetic acid, monohydrate
Canonical SMILES[H]N1C[C@H](C(C)=C)[C@H](CC(O)=O)[C@H]1C(O)=O.O
分子式C10H15NO4o H2O
分子量231.2
溶解度50mg/ml in PBS
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述
Kainic acid is a natural marine product originally isolated from the red marine alga D. Simplex. It is a potent central nervous system stimulant, and has been developed as the prototype neuroexcitatory amino acid for the induction of seizures in experimental animals, at a typical dose of 10-30 mg/kg in mice.[1] Kainic acid is neuroexcitotoxic and epileptogenic, acting through specific kainate receptors.[2]

Reference:
[1]. Marsicano, G., Goodenough, S., Monory, K., et al. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302(5642), 84-88 (2003).
[2]. Ferkany, J.W., Zaczek, R., and Coyle, J.T. Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors. Nature 298(19), 757-759 (1982).