[登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > Eliapixant
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Eliapixant
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Eliapixant图片
CAS NO:1948229-21-7
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
Eliapixant (BAY 1817080) 是一种有效和选择性的 P2X3 受体拮抗剂，IC50 值为 8 nM。Eliapixant 可用于难治性慢性咳嗽的研究。
Cas No.1948229-21-7
别名依利哌嗪,BAY 1817080
分子式C22H21F3N4O3S
分子量478.49
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

Eliapixant can be used for the research of coughs and diabetes complications[1].

[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.
[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240.