| CAS NO: | 645-33-0 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 645-33-0 |
| 别名 | 4-甲氧基多巴胺盐酸盐 |
| Canonical SMILES | OC1=CC(CCN)=CC=C1OC.Cl |
| 分子式 | C9H13NO2 • HCl |
| 分子量 | 203.7 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-hydroxy-4-Methoxyphenethylamine is a metabolite of the catecholamine dopamine .1It is formed from dopamine by catechol-O-methyltransferase (COMT). 3-hydroxy-4-Methoxyphenethylamine (200 µM) decreases the viability of SH-SY5Y cells.2It induces tachycardia and increases blood pressure in normotensive or DOCA-salt hypertensive rats when administered at a dose of 1 mg/kg.33-hydroxy-4-Methoxyphenethylamine (100 mg/kg) induces tremors and rigidity in mice.4 1.Shoup, R.E., Davis, G.C., and Kissinger, P.T.Determination of catechol-O-methyltransferase activity in various tissues by liquid chromatographyAnal. Chem.52(3)483-487(1980) 2.Haque, M.E., Asanuma, M., Higashi, Y., et al.Apoptosis-inducing neurotoxicity of dopamine and its metabolites via reactive quinone generation in neuroblastoma cellsBiochim. Biophys. Acta1619(1)39-52(2003) 3.Gregson, R.P., Lohr, R.R., Marwood, J.F., et al.3-Hydroxy-4-methoxyphenethylamine, the cardioactive constituent of a soft coralExperientia37(5)493-494(1981) 4.Spoerlein, M.T., and VanderWende, C.Nature of the tremors induced by p-methoxydopamineLife Sci.6(19)2029-2035(1967) |
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