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Paltusotine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Paltusotine图片
CAS NO:2172870-89-0
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
Paltusotine (CRN00808) 是一种具有口服活性的，非肽选择性生长抑素 2 型 (SST2) 受体激动剂。Paltusotine 具有在长效生长抑素受体配体作用后维持 GH 和 IGF-1 水平的潜力。
Cas No.2172870-89-0
别名CRN00808
分子式C27H22F2N4O
分子量456.49
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy[1][2].

[1]. Murray B. Gordon, et al. Identification of a dose range for once daily oral paltusotine in patients with acromegaly that maintains IGF-1 levels when switching from long-acting somatostatin receptor ligand therapy. Endocrine Abstracts (2021) 73 OC15.4.
[2]. Rosa Luo, et al. Pharmacokinetics and Safety of an Improved Oral Formulation of Paltusotine, a Selective, Non-Peptide Somatostatin Receptor 2 (SST2) Agonist for the Treatment of Acromegaly. Journal of the Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021.