| CAS NO: | 2653994-08-0 |
| 包装: | 5mg |
| 市场价: | 13320元 |
| Cas No. | 2653994-08-0 |
| 别名 | NVP-JDQ443 |
| 分子式 | C29H28ClN7O |
| 分子量 | 526.03 |
| 溶解度 | DMSO : 250 mg/mL (475.26 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | JDQ-443 (example 1a) is a covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1)[1]. JDQ-443 (NVP-JDQ443) traps the GDP-bound inactive conformation of KRAS[1]. [1]. LIU BO, et al. PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS. Patent WO2021120890A1. |
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