JBSNF-000088 (JBSNF 000088; JBSNF000088), a nicotinamide analog, is a potent inhibitor of Nicotinamide N-methyltransferase (NNMT) with the potential to treat metabolic disorders such as obesity. In mice with high fat diet (HFD)-induced obesity, JBSNF-000088 treatment caused a reduction in body weight, improved insulin sensitivity and normalized glucose tolerance to the level of lean control mice.

纯度：≥98%

CAS： 7150-23-4