| CAS NO: | 84472-85-5 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Cas No. | 84472-85-5 |
| 别名 | 3'-叠氮-2',3'-双脱氧尿苷 |
| Canonical SMILES | O=C1N([C@@]2([H])C[C@@H]([C@H](O2)CO)N=[N+]=[N-])C=CC(N1)=O |
| 分子式 | C9H11N5O4 |
| 分子量 | 253.2 |
| 溶解度 | DMF: 2 mg/ml,DMSO: 2 mg/ml,Ethanol: insol,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3’-Azido-2’,3’-dideoxyuridine (AZddU) is an antiviral nucleoside analog.1It is phosphorylated by thymidine kinase.2AZddU inhibits cytopathogenicity induced by HIV or Moloney sarcoma virus (MSV) in MT-4 cells (EC50s = 0.36 and 15 µM, respectively).1 1.Balzarini, J., Baba, M., Pauwels, R., et al.Anti-retrovirus activity of 3’-fluoro- and 3’-azido-substituted pyrimidine 2’,3’-dideoxynucleoside analoguesBiochem. Pharmacol.37(14)2847-2856(1988) 2.Eriksson, B.F., Chu, C.K., and Schinazi, R.F.Phosphorylation of 3’-azido-2’,3’-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5’-triphosphateAntimicrob. Agents Chemother.33(10)1729-1734(1989) |
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