| CAS NO: | 1637542-34-7 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 1637542-34-7 |
| Canonical SMILES | ClC1=C(C(O)C2=NN=C(OC)C=C2)C=C(C3=C4C=CC(N5CCOCC5)=CC4=NC=N3)C(F)=C1 |
| 分子式 | C24H21ClFN5O3 |
| 分子量 | 481.91 |
| 溶解度 | DMSO : ≥ 100 mg/mL (207.51 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Rac-Nedisertib (Rac-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of<3 nM[1]. DNA-PK|<3 nM (IC50) Rac-Nedisertib (Compound 137) potently inhibits DNA-PK, with an IC50 of<3 nM for DNA-PK, 0.5-5 μM for cellular pDNA-PK and 15-25 μM for KV11.1 (hERG, human ether a-go-go related gene) ).[1]. [1]. Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1. |
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