| CAS NO: | 13405-60-2 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 13405-60-2 |
| 别名 | 1-没食子酸酰葡萄糖 |
| Canonical SMILES | O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO |
| 分子式 | C13H16O10 |
| 分子量 | 332.3 |
| 溶解度 | DMF: 14 mg/mL,DMSO: 12 mg/mL,PBS (pH 7.2): 0.30 mg/mL |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | β-Glucogallin is a plant metabolite that has been found inE. officinalisand an aldose reductase 2 inhibitor (IC50= 17 µM).1β-Glucogallin (30 µM) inhibits glucose-induced sorbitol accumulation in lenses isolated from a transgenic mouse model overexpressingAKR1B1, the gene encoding human aldose reductase 2. It also reduces methylglyoxal-induced increases in COX-2, IL-6, IL-8, chemokine (C-C motif) ligand 2 (CCL2), and receptor for advanced glycation end products (RAGE) levels in ARPE-19 retinal epithelial cells.2 1.Puppala, M., Ponder, J., Suryanarayana, P., et al.The isolation and characterization of β-glucogallin as a novel aldose reductase inhibitor from Emblica officinalisPLoS One7(4)e31399(2012) 2.Ma, Y., Liu, F., and Xu, Y.Protective effect of β-glucogallin on damaged cataract against methylglyoxal induced oxidative stress in cultured lens epithelial cellsMed. Sci. Monit.259310-9318(2019) |
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