Izilendustat

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Izilendustat

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1303512-02-8

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
50mg	电议
100mg	电议

产品介绍

Izilendustat 是一种有效的脯氨酰羟化酶 (prolyl hydroxylase) 抑制剂，可稳定缺氧诱导因子-1 α (HIF-1α) 和缺氧诱导因子-2 (HIF-2)。Izilendustat 具有研究与身体免疫反应相关的疾病的潜力，如结肠炎和其他炎症性肠病 (提取自专利 WO2011057115A1 和 WO2011057121A1)。

Cas No.	1303512-02-8
分子式	C22H28ClN3O4
分子量	433.93
溶解度	DMSO : 25 mg/mL (57.61 mM; ultrasonic and warming and heat to 60℃)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Izilendustat is a potent inhibitor of prolyl hydroxylase which can stabilize hypoxia inducible factor- 1 alpha (HIF- lα) and hypoxia inducible factor-2 (HIF-2). Izilendustat has the potential for researching diseases that relate to the body’s inmmune response like colitis and other inflammatory bowel diseases (extracted from patent WO2011057115A1 and WO2011057121A1)[1][1]. [1]. Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1. [2]. Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.