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3,6-Dihydroxyflavone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3,6-Dihydroxyflavone图片
CAS NO:108238-41-1
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
3,6-Dihydroxyflavone 是一种抗癌剂。3,6-Dihydroxyflavone 剂量和时间依赖性地降低细胞活力并通过激活半胱天冬酶级联、切割聚 (ADP-核糖) 聚合酶 (PARP) 诱导 apoptosis。3,6-Dihydroxyflavone 增加细胞内氧化应激和脂质过氧化。
Cas No.108238-41-1
别名3,6-二羟基黄酮,3,6-DHF
分子式C15H10O4
分子量254.24
溶解度DMSO : 66.67 mg/mL (262.23 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1].

[1]. Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648(1-3):31-38.