| CAS NO: | 121080-63-5 |
| 包装: | 1mg |
| 市场价: | 6706元 |
| Cas No. | 121080-63-5 |
| 别名 | SN-38葡糖苷酸,SN-38G |
| Canonical SMILES | CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)C=C51 |
| 分子式 | C28H28N2O11 |
| 分子量 | 568.5 |
| 溶解度 | DMSO: slightly soluble,Methanol: slightly soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SN-38 Glucuronide is a phase II metabolite of irinotecan .1It is formedviaglucuronidation of the irinotecan phase I metabolite SN-38 by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1. 1.Hirose, K., Kozu, C., Yamashita, K., et al.Correlation between plasma concentration ratios of SN-38 glucuronide and SN-38 and neutropenia induction in patients with colorectal cancer and wild-type UGT1A1 geneOncol. Lett.3(3)694-698(2012) |
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