| CAS NO: | 1448345-60-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 1448345-60-5 |
| 别名 | 阿苯哒唑砜-D3 |
| Canonical SMILES | CCCS(=O)(C1=CC=C(N=C(N2)NC(OC([2H])([2H])[2H])=O)C2=C1)=O |
| 分子式 | C12H12D3N3O4S |
| 分子量 | 300.3 |
| 溶解度 | DMF: 1 mg/ml,DMSO: slightly,Ethanol: insol,PBS (pH 7.2): insol |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Albendazole sulfone-d3is intended for use as an internal standard for the quantification of albendazole sulfone by GC- or LC-MS. Albendazole sulfone is an active metabolite of the benzimidazole anthelmintic albendazole .1,2It inhibits spore formation ofE. hellem, E. cuniculi, andE. intestinalis in vitro(IC90s =<0.0001,<0.001, and<0.1 µg/ml, respectively).2 1.BaliharovÁ, V., VelÍk, J., FimanovÁ, K., et al.Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitroPharmacol. Rep.5797-106(2005) 2.Ridoux, O., and Drancourt, M.In vitro susceptibilities of the microsporidia Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon intestinalis to albendazole and its sulfoxide and sulfone metabolitesAntimicrob. Agents and Chemother.42(12)3301-3303(1998) |
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