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β,β-Dimethylacrylshikonin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
β,β-Dimethylacrylshikonin图片
CAS NO:24502-79-2
包装与价格：
包装价格(元)
5mg电议
10mg电议
20mg电议

产品介绍
β,β-Dimethylacrylshikonin 是从 Arnebia nobilis 中提取得到的一种萘醌衍生物，通过PI3K通路诱导 eNOS、VEGF 和 HIF-1α 的表达，促进血管生成。Arnebin 1 具有抗肿瘤活性。
Cas No.24502-79-2
别名(β,β-二甲基丙烯酰基)紫草素,Isoarnebin I
Canonical SMILESO=C1C2=C(O)C=CC(O)=C2C(C=C1[C@@H](C/C=C(C)/C)OC(/C=C(C)/C)=O)=O
分子式C21H22O6
分子量370.4
溶解度DMSO: 25 mg/mL (67.49 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

β,β-Dimethylacrylshikonin is a naphthoquinone derivative isolated from Arnebia nobilis, promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Arnebin 1 has anti-tumor activity[1].

[1]. Zeng Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015 Sep;36(3):685-97. [2]. Sidhu GS, et al. Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing. J Invest Dermatol. 1999 Nov;113(5):773-81.