| CAS NO: | 2260886-64-2 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 2260886-64-2 |
| 分子式 | C33H41ClN8O2 |
| 分子量 | 617.18 |
| 溶解度 | DMSO : 12.5 mg/mL (20.25 mM; Need ultrasonic) |
| 储存条件 | 4°C, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | JND3229 is a highly potent and fourth-generation EGFRC797S reversible inhibitor with IC50 value of 5.8 nM, and also potently suppressed EGFRL858R/T790M and EGFRWT with IC50 values of 30.5 and 6.8 nM. [1]. Lu X, et al. Discovery of JND3229 as a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy. ACS Med Chem Lett. 2018 Oct 8;9(11):1123-1127. |
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