CD40-TRAF6 inhibitor (TRAF-STOP inhibitor 6877002) is a novel and potent inhibitor of CD40-TRAF6 protein protein interaction with the potential for treating atherosclerosis. It inhibits NF-κB activation in RAW cells, prevents the progression of established atherosclerosis in mice, reduces leukocyte recruitment and reduces macrophage activation, and reduces macrophage proliferation in atherosclerotic plaques.

纯度：≥98%

CAS：433249-94-6