AFN-1252 tosylate (AFN-12520000; API-1252; Debio-1452), the tosylate salt of AFN1252, is a novel and potent inhibitor of enoyl-(acyl-carrier protein) reductase Fabl with the potential for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, orally bioavailable absorption, long elimination half-live and efficacy in animal models. AFN-1252 displays a Staphylococcus-specific spectrum of activity.

纯度：≥98%

CAS：1047981-31-6