Namitecan (ST-1968) is a novel, potent and water-soluble camptothecin analog with high antitumor activity, acting as a topoisomerase I inhibitor. ST1968 exhibited an impressive activity against several tumors including models of ovarian and colon carcinoma in which a high rate of cures was observed. t ST1968 was able to overcome the most relevant mechanisms associated with the development of topotecan resistance (i.e., slow proliferation and target downregulation) owing to its peculiar pharmacokinetic behaviour.

纯度：≥98%

CAS：372105-27-6