Fluorofenidone(AKF-PD; AKFPD), a derivative of AMR69, a promising multifunctional antifibrosis pyridinone drug which act as a potent inhibitor of nicotinamide adeninedinucleotide phosphate oxidase via PI3K/Akt pathway in the pathogenesis of renal interstitial fibrosis. It attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway.

纯度：≥98%

CAS：848353-85-5