Ercalcitriol (RO-17-6218 or 1,25-dihydroxyvitamin D2, 1α,25-Dihydroxy Vitamin D2) is the active metabolite and circulating form of vitamin D2 formed by 25-hydroxylase in the liver and 25-hydroxyvitamin D-hydroxylase in the kidney. By binding to the vitamin D receptor (VDR), 1,25-dihydroxy Vitamin D2 activates VDR to interact with the retinoid X receptor (RXR), forming the VDR/RXR/cofactor complex, which regulates gene transcription.

纯度：≥98%

CAS：60133-18-8