EPZ-031686 (EPZ031686) is a potent, selective and orally bioavailable SMYD3 (Set and Mynd Domain containing 3) inhibitor with potential antitumor activity. It inhibits SMYD3 with an IC50 of 3 nM in enzymatic/cell-free assay. SMYD3 is a lysine methyltransferase overexpressed in many different cancer histologies, and is reported to be associated with a poor clinical prognosis.

纯度：≥98%

CAS：1808011-22-4