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SBE 13 HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SBE 13 HCl图片
CAS NO:1052532-15-6
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
SBE-13, SBE 13
产品介绍

生物活性

SBE 13 HCl是PLK1的选择性抑制剂,对于PLK1,PLK3和PLK2,IC 50值分别为200pM,875nM和66μM。

靶点信息

PLK1PLK3PLK2
200 pM875 nM>66 μM

化学数据

目录号A14426
作用机制Inhibitor (抑制剂)
M. Wt479.4
FormulaC24H27ClN2O4.HC
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1052532-15-6
SynonymsSBE-13, SBE 13
SMILESCOC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl

溶解度

In vitroDMSO90 mg/mL (187.73 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM20.86 mL104.3 mL208.59 mL
0.5 mM4.17 mL20.86 mL41.72 mL
1 mM2.09 mL10.43 mL20.86 mL
5 mM0.42 mL2.09 mL4.17 mL

*The above data is based on the productmolecular weight 479.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.