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Molidustat
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Molidustat图片
CAS NO:1154028-82-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
BAY 85-3934, BAY85-3934, BAY853934
产品介绍

生物活性

Molidustat是一种新型的低氧诱导因子(HIF)脯氨酰羟化酶(PH)抑制剂,可刺激促红细胞生成素(EPO)的产生和红细胞的形成。

靶点信息

PHD2PHD3PHD1
280 nM450 nM480 nM

化学数据

目录号A14404
作用机制Inhibitor (抑制剂)
M. Wt314.3
FormulaC13H14N8O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1154028-82-6
SynonymsBAY 85-3934, BAY85-3934, BAY853934
SMILESC1COCCN1C2=NC=NC(=C2)N3C(=O)C(=CN3)N4C=CN=N4

溶解度

In vitroDMSOWarmed: 3 mg/mL (9.54 mM)
WaterInsoluble
EthanolDMF: 4 mg/mL (12.72 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM31.82 mL159.08 mL318.17 mL
0.5 mM6.36 mL31.82 mL63.63 mL
1 mM3.18 mL15.91 mL31.82 mL
5 mM0.64 mL3.18 mL6.36 mL

*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.