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重组跨膜蛋白173
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组跨膜蛋白173(TMEM173)
Recombinant Sting1
产品介绍
基因名:

Sting1


产品别名:

2610307O08Rik; ERIS; MPYS; Mita; STING; STING-beta; Tmem173; Sting1; stimulator of interferon response cGAMP interactor 1; stimulator of interferon response cGAMP interactor 1; stimulator of interferon genes protein; endoplasmic reticulum interferon stimulator; mediator of IRF3 activation; mitochondrial mediator of IRF3 activation; stimulator of interferon protein; transmembrane protein 173; 跨膜蛋白173; 跨膜蛋白173(TMEM173);


背景信息:
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。