重组酪蛋白激酶21

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重组酪蛋白激酶21

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant PLEKHO1
Recombinant pleckstrin homology domain containing O1 protein

产品介绍

基因名：

PLEKHO1

产品别名：

CKIP-1； CKIP1； JBP； OC120； PLEKHO1； pleckstrin homology domain containing O1； pleckstrin homology domain containing O1； pleckstrin homology domain-containing family O member 1； C-Jun-binding protein； CK2 interacting protein 1; HQ0024c protein； CK2-interacting protein 1； PH domain-containing family O member 1； casein kinase 2-interacting protein 1； osteoclast maturation-associated gene 120 protein；酪蛋白激酶21；

背景信息：

Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2(CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。