Selgantolimod (formerly GS-9688; GS9688) is a novel, potent, selective and orally bioactive toll-like receptor 8 (TLR8) agonist with the potential for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection. The potent TLR8 agonism (IL-12p40 EC50 =220 nM) and >100-fold TLR7 selectivity (IFN-α EC50 > 50 μM) was observed in human peripheral blood mononuclear cells (PBMCs).

纯度：≥98%

CAS：2004677-13-6