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重组70kDa热休克蛋白5(HSPA5)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
重组70kDa热休克蛋白5(HSPA5)真核蛋白
Recombinant HSPA5
产品介绍
基因名：

HSPA5


产品别名：

BIP； GRP78； HEL-S-89n； HSPA5； heat shock protein family A (Hsp70) member 5； heat shock protein family A (Hsp70) member 5； endoplasmic reticulum chaperone BiP； 78 kDa glucose-regulated protein； HSP70 family protein 5； binding-immunoglobulin protein； endoplasmic reticulum lumenal Ca(2+)-binding protein grp78； epididymis secretory sperm binding protein Li 89n； glucose-regulated protein, 78kDa； heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)； heat shock protein 70 family protein 5； heat shock protein family A member 5； immunoglobulin heavy chain-binding protein； 70kDa热休克蛋白5(HSPA5)； 70kDa热休克蛋白5(HSPA5)真核蛋白； 葡萄糖调节蛋白78； 葡萄糖调节蛋白78/热休克蛋白70蛋白5；


背景信息：
The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of 70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP 94) and protein disulfide isomerase (PDI). The presence of carboxy terminal KDEL appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。