SAR191801 (hPGDS-IN-1) is a novel, potent and selecive hPGDS inhibitor with an IC50 of 12 nM in the Fluorescence Polarization Assay (the EIA assay). Hematopoietic prostaglandin D synthase (HPGDS) is primarly expressed in mast cells, antigen-presenting cells, and Th-2 cells. HPGDS converts PGH2 into PGD2, a mediator thought to play a pivotal role in airway allergy and inflammatory processes.

纯度：≥98%

CAS：1234708-04-3