Rodatristat, used as a prodrug (rodatristat ethyl), is a novel, potent, orally bioavailable direct and reversible tryptophan hydroxylase 1 (TPH1) inhibitor with the potential for treatment of pulmonary arterial hypertension. Its molecular structure was designed to prevent it from crossing the blood-brain barrier, thereby restricting its effect to peripheral serotonin. Indeed, in nonclinical studies rodatristat did not lower CNS levels of serotonin.

纯度：≥98%

CAS：1673568-73-4