DHODH-IN-16 是一种有效的二氢乳清酸脱氢酶 (DHODH) 抑制剂，对人 DHODH 的 IC50 为 0.396 nM。
货号:ajcx35896
CAS:2511248-11-4
分子式:C24H25FN4O3
分子量：436.48
溶解度:DMSO : 100 mg/mL (229.11 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].

DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM[1].

[1]. Scott Kuduk, et al. Dihydroorotate dehydrogenase inhibitors. WO2020212897A1.