DB550，靶向作用 PLCγ1，可破坏 CD95-PLCγ 1 之间的作用，抑制 Th17 驱动的炎症，而不影响 CD95-FADD 之间的作用。
货号:ajcx13842
CAS:N/A
分子式:C53H87F15N18O18S
分子量：1581.41
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DB550 targets PLCγ1 and disrupts the CD95-PLCγ 1 interaction to prevent Th17-driven inflammation, without affecting the CD95-FADD interaction[1]. PLCγ1[1].

[1]. Poissonnier A, et al. Disrupting the CD95-PLCγ1 interaction prevents Th17-driven inflammation. Nat Chem Biol. 2018 Dec;14(12):1079-1089.