PG106 TFA 是一种有效的、选择性的 hMC3 receptor 拮抗剂 (IC50= 210 nM)，对 hMC4 受体(EC50=9900 nM) 和 hMC5 受体无活性。
货号:ajcx36302
CAS:N/A
分子式:C53H70F3N13O11
分子量：1122.2
溶解度:DMSO : 25 mg/mL (22.28 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PG106 TFA is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50= 210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].

[1]. Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides